The Texans dropped their home opener. Houston lost to the AFC South rival Indianapolis Colts 31-20 at NRG Stadium. C.J. Stroud completed 30-of-47 passes for 384 yards and two touchdowns. Nico Collins led the way for Houston's receivers with seven receptions for 146 yards and a score. Tank Dell scored his first career TD on a 23-yard catch in the fourth quarter. The Texans fell to 0-and-2. They will go on the road to face the Jacksonville Jaguars next Sunday afternoon.