Arizona vs. Houston Football Prediction & Odds - Oct. 18

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The Arizona Wildcats (4-2) meet a conference opponent when they visit the Houston Cougars (5-1) on Saturday, October 18, 2025 at TDECU Stadium in a Big 12 clash.

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Arizona vs. Houston Matchup Info

  • Game date: Saturday, October 18, 2025
  • Game time: 12 p.m. ET
  • Location: Houston, Texas
  • Venue: TDECU Stadium
  • TV channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Arizona vs. Houston Odds and Prediction

  • Spread favorite: Wildcats (-1.5)
  • Moneyline: Wildcats (-114), Cougars (-105)
  • Total: 47.5 points
  • Pick ATS: Houston (+1.5)
  • Pick OU: Over (47.5)
  • Prediction: Houston 27, Arizona 23

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Arizona vs. Houston Betting Records and Insights

  • Arizona has won three games against the spread this season, while failing to cover twice.
  • Houston has covered four times in six matchups with a spread this season.
  • The Wildcats have won each of their two games this season when playing as at least 1.5-point favorites.
  • The Cougars have not covered the spread when an underdog by 1.5 points or more this season (in one opportunity).
  • This season, games featuring the Arizona have hit the over twice.
  • Houston games have gone over the point total four out of six times this season.

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